Dr. Gleeson's work focuses on the development of tools and standards to facilitate the generation, analysis and sharing of models of neuronal systems. He developed neuroConstruct, an open source graphical application for constructing and analysing 3D networks of biophysically detailed neurons.
He is also the main technical contributor to the NeuroML language for simulator independent model descriptions in neuroscience. He is leading development of the Open Source Brain repository which aims to facilitate the sharing of data in neuroscience and the collaborative development of neuronal models in an open source environment.
His research activities include investigation of information processing in cerebellar and cortical microcircuits. He is also Project Director of the OpenWorm project, which aims to create an in-silico, cell by cell model of the nematode C. elegans.
More recently he has co-founded an international collaboration, ModECI (Model Exchange and Convergence Initiative), which aims to unify representations of computational models across the fields computational neuroscience, cognitive science and machine learning.
Dr. Sinha is contributing to the Kavli Foundation funded project "Tools and standards for single-cell modeling in neuroscience". He is also a key contributor to the NeuroML model development language and the Open Source Brain initiative.
Project title: Development and standardisation of biophysically detailed models of neurons and muscles of C. elegans
Project title: Use of fine-tuned Large Language Models to constrain and validate computational models of C. elegans
Project title: Consolidating neuroinformatics resources related to C. elegans connectomics
Project title: Modelling Human Neural Circuits Across Scales of Complexity
Members of the lab have been actively involved in the Google Summer of Code program, through the INCF organisation.
Members of the lab have been mentors in the Outreachy program as part of ModECI - the Model Exchange and Convergence Initiative.
Please get in contact if you would like to discuss working with the lab in any of these ways.